The Indian Institute of Science Education and Research (IISER) Kolkata was founded in 2006 as part of the IISER system created by the Ministry of Education to achieve excellence in the basic sciences, and was accorded the status of an Institute of National Importance in 2012. Its campus is at Mohanpur in West Bengal.

The institute has seven departments: physical sciences; chemical sciences; biological sciences; earth sciences; mathematics and statistics; computational and data sciences; and humanities and social sciences. It also runs four research centres, including the Centre of Excellence in Space Sciences India and the National Centre for High-Pressure Studies. Its flagship programme is the BS-MS degree. Its NIRF 2026 data submission reports 1,189 UG and PG students and 602 full-time PhD scholars in 2024-25.