The Indian Institute of Science Education and Research (IISER) Bhopal was established in 2008, and its foundation stone was laid by Arjun Singh on 8 October 2008. It is on Bhopal Bypass Road, Bhauri, in Madhya Pradesh, on a 200-acre campus. Its Act and Statutes page lists the NITSER Act and the First Statutes of IISERs.

The institute has 10 departments and three centres of excellence, and awards BS, BTech, BS-MS, MA, MSc, integrated PhD and PhD degrees. Its At a Glance page lists 2,874 students: 1,971 undergraduate, 114 postgraduate and 789 PhD. Professor Raghuvir Singh Tomar has been Director Incharge since 19 June 2026, after Professor Gobardhan Das’s term ended on 8 June 2026, and the institute is recruiting a director.